Foundation Science of Exosomes Book

A scientific textbook on exosome biology, from molecular mechanisms to clinical translation.

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Foundation Science of Exosomes book cover

What This Book Covers

  • Chapter 1 – What Exosomes Are and Why They Matter

    Structural anatomy, lipidomic membrane dynamics, extracellular particle classification

  • Chapter 2 – Historical Evolution of Exosome Biology

    From platelet dust to MISEV2023 guidelines and modern translational kits

  • Chapter 3 – Biogenesis and Secretion of Exosomes

    ESCRT pathways, MVB formation, intraluminal vesicle release mechanisms

  • Chapter 4 – Cargo Sorting, Molecular Packaging, and Composition

    Proteins, RNA, DNA, lipids, post-translational modifications, proteomics

  • Chapter 5 – Isolation, Enrichment, Characterization, and Quality Control

    Pre-analytics, orthogonal characterization, functional assays, MISEV2018/2023 standards

  • Chapter 6 – Biodistribution and Routes of Administration

    Organotropism, integrin code, blood-brain barrier, therapeutic design implications

  • Chapter 7 – Exosomes in Normal Physiology

    Hematopoiesis, CNS, cardiovascular, reproductive biology, stem cell niches

  • Chapter 8 – Disease Biology and Regenerative Applications

    Cancer, neurodegeneration, inflammation, wound healing, MSC-derived exosome therapy

  • Chapter 9 – Diagnostics, Therapeutic Engineering, and Regulatory Translation

    Liquid biopsy, therapeutic engineering, GMP manufacturing, FDA/EMA regulatory pathways

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Foundation Science of Exosomes: Biogenesis, Characterization, Clinical Translation and Regenerative Applications

  • Covers the complete spectrum from molecular mechanisms to clinical translation.

  • Nine chapters, from exosome biogenesis to diagnostics and regulatory pathways.

  • Aligned with MISEV2018 and MISEV2023 guidelines of the International Society for Extracellular Vesicles (ISEV).

  • Written for postgraduate students, clinicians, researchers and biotechnology professionals.

About the Book

Biogenesis, Characterization, Clinical Translation and Regenerative Applications

A comprehensive scientific textbook on extracellular vesicle biology - covering the complete spectrum from molecular mechanisms to clinical translation. Written for postgraduate students, clinicians, researchers, and biotechnology professionals in regenerative medicine, diagnostics, and biomedical product development.

Authors: Dr. Leroy Rebello, Dr. Sreesudha Chepyala, Dr. Pratiksha Palahe

Foreword: Dr. Pratiksha Palahe, Chief Scientific Officer, Biotex Life Solutions Pvt Ltd

Publisher: Biotex Life Solutions Pvt Ltd

Pages: 190

Published: May 2026

Format: Print book

Guidelines: Aligned with MISEV2018 and MISEV2023 (ISEV)

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  • The information and articles on our website are meant for educational purposes only and are not meant as a substitute for the professional advice of your doctor or healthcare professional.

  • They are not intended to diagnose, treat, cure or prevent any disease, and results may vary from individual to individual.

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Designed as a nutritional supplement and not as a medicine.